cornea interface tear film

Ocular Science · Pharma & Cosmetics · In Vitro + In Silico

Reduce ocular irritation risk before it delays
your product

Eyveris helps pharmaceutical and cosmetics teams detect ocular irritation risk, compatibility issues, and formulation weaknesses early using an integrated in vitro and in silico tear film and cornea testing platform.

Discuss Your Formulation Challenge See How the Platform Works
10+
Years of Underlying Research
2
Integrated Model Platforms
100%
Animal-Free Methodologies
4
Co-founders, all PhD Scientists
Collaboration areas
Ophthalmic Pharma Cosmetic & Periocular OTC Lubricants Biocompatible Implants Contact Lens Systems Drug Nanocarriers
lipid aqueous Tear Film glycocalix Corneal Surface lipid adsorption implant surface Implantable Material lipid layer In Silico Modeling

About Eyveris

Tear film and cornea testing for
better formulation decisions

Eyveris is a research-driven startup built on over 10 years of work in tear film biophysics, corneal surface science, and interfacial phenomena. We turn that science into practical testing tools for pharmaceutical and cosmetics companies developing ocular, periocular, and ocular-exposed products.

For pharmaceutical teams, our platform supports earlier identification of irritation and compatibility risks, helping reduce late-stage reformulation and development uncertainty. For cosmetics teams, it provides independent, science-based evidence for eye-area compatibility and low-irritation positioning.

We operate at the intersection of academic rigor and industrial relevance delivering reproducible, interpretable results that support formulation decisions, technical discussions, and regulatory-facing documentation.

Animal-Free Peer-Reviewed Methods Regulatory-Compatible EU Cosmetics Regulation–Aware Prague, CZ

Services

How we help

Testing and R&D support built around our tear film and cornea models, tailored to your product type, development stage, and decision needs.

Ocular Safety & Irritation

Mechanistic, quantitative assessment of tear film destabilization and breakup using fully animal-free, reproducible methods.

"Find irritation-related formulation risks before they become expensive development problems."

Formulation Development

Understand how excipients, preservatives, polymers, and delivery systems interact with the tear film and corneal surface.

"Choose ingredients and formulation strategies based on evidence, not trial and error."

Biocompatibility Testing

Assess implants, contact lens materials, cosmetic ingredients, and related materials against the ocular lipid environment.

"Generate independent evidence that your materials do not compromise ocular surface health."

Technology Platform

An integrated platform for
earlier, better formulation decisions

In Vitro

Tear Film Platform

A proprietary acellular tear film interface that helps quantify how formulations interact with, destabilize, or preserve tear film structure under controlled conditions.

  • Quantify tear film destabilization and breakup
  • Track structural changes at the ocular interface
  • Simulated blinking cycles
  • Assess drug partitioning between lipid and aqueous tear layers
In Vitro

Corneal Interface Platform

A glycocalyx-relevant corneal interface model designed to reveal irritation-related and compatibility-related interactions at the ocular surface.

  • Assess corneal surface compatibility
  • Understand polymer-cornea interactions
  • Profile preservative-related mechanisms
  • Screen materials and formulations for biocompatibility risk
In Silico

Molecular Dynamics Simulations

Coarse-grained and atomistic molecular dynamics simulations that explain formulation behavior at molecular resolution and help troubleshoot problems that experiments alone cannot fully resolve.

  • Reveal drug-lipid and excipient-lipid interactions
  • Study nanocarrier behavior, passage, and decomposition
  • Clarify mechanisms at molecular resolution
  • Support rational formulation troubleshooting
Data & Software

Proprietary Analysis Pipelines

Standardized analysis workflows, software tools, and reporting methods that turn complex ocular-interface data into reproducible, interpretable, and decision-ready results.

  • Automated quantification of destabilization effects
  • Standardized reporting workflows
  • Custom software for ocular-interface data
  • Documentation suitable for technical and regulatory discussions
◆

The first integrated in vitro + in silico platform dedicated to ocular formulation testing, combining tear film and cornea models with mechanistic simulations, specialized analysis, and standardized workflows.

Our Team

Scientists who understand
both worlds

Prof. Lukasz Cwiklik
Prof. Lukasz Cwiklik
CEO

Expert in tear film biophysics and molecular simulations, with 15+ years of research focused on ocular surface mechanisms, formulation interactions, and translational science.

Dr. Katarina Vazdar
Dr. Katarina Vazdar
CSO

Surface and interface chemistry specialist with expertise in lipid membrane systems, ocularly relevant interfaces, and formulation-related interactions.

Dr. Wojciech Pajerski
Dr. Wojciech Pajerski
CTO

Leads platform development, analytical methods, and software workflows, with focus on reproducibility, data quality, and experimental decision support.

Dr. Martin Kubeš
Dr. Martin Kubeš
CBO

Leads partnerships and commercial development, translating scientific capabilities into industry collaborations and customer-focused programs.

Applications

Where our platform creates value

Pharmaceutical

Ophthalmology

  • Artificial tears and OTC lubricants
  • Prescription eye drops, including glaucoma and dry-eye formulations
  • Nanocarrier formulations for ocular drug delivery
  • Preservative selection and strategy
  • Excipient screening and mechanism-based profiling
Cosmetics & Consumer

Periocular Products

  • Cosmetics with ocular or periocular exposure
  • Artificial eyelashes, glues, and removers
  • Independent support for low-irritation and eye-area compatibility claims
  • Benchmarking against competitor formulations
  • Assessment of microplastic-related ocular surface impact

Reference Work

Built on peer-reviewed science

Drug Delivery Systems

Latanoprost Formulations

Comparative analysis of delivery systems and their effects on tear film lipid layer stability, linking formulation design choices to ocular surface behavior and likely tolerability implications.

Preservative Safety

BAK Mechanism of Action

Mechanistic evaluation of benzalkonium chloride effects on tear film lipid structure and function, supporting more informed preservative strategy decisions.

Molecular Interactions

Drug–Lipid Incorporation

Combined in vitro and in silico analysis of drug integration into tear film lipids, revealing interactions relevant to both tolerability and performance.

Biocompatibility

Polymer–Lipid Interactions

Biocompatibility-focused assessment of polymer interactions with biological environments, helping evaluate material compatibility for implants and devices.

Contact

Let's talk about
your formulation challenge

Whether you are screening early candidates, comparing formulations, or investigating a specific compatibility problem, we can scope a study around your technical and development needs.

Location
Prague, Czech Republic
Address
Dolejškova 2155/3
Email
contact@eyveris.com
Registration
Eyveris s.r.o. · IČO 24490580